Penyebab Perubahan Ketebalan Carotid Intima-Media

Budi Arief Waskito

Abstract


Atherosclerosis causes significant morbidity and mortality. Carotid intima-media thickness (CIMT) can predict the onset of cardiovascular and ischemic stroke in the future. CIMT, the measurement of atherosclerosis, is determined in vivo using carotid ultrasound. CIMT is associated with traditional cardiovascular risk factors such as age, sex, race, smoking habits, alcohol consumption, exercise habits, blood pressure, dyslipidemia, dietary patterns, medications used, glycemia, hyperuricemia, anthropometric parameters associated with obesity. In addition, CIMT is also associated with novel risk factors, ie genotypes, cardiovascular anthropometry parameters, rheumatoid arthritis, immunologic diseases, inflammatory cytokines, lipid peroxidation, chemocyte anthropometric parameters, infectious diseases, vitamin D, matrix metalloproteinases, and other diseases

Keywords


Ultrasound; Aterosclerosis; Pheripheral Vascular; Carotid intima-media thickness; Cardiovasculer and Cerebrovasculer; risk factors

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References


Corrales A, Parra JA, Gonzale-Juanatey C, Rueda-Gotor J, Blanco R, Llorca J, et al., 2013. Cardiovascular risk stratificationin rheumatic diseases: carotid ultrasound is more sensitive than Coronary Artery Calcification Score to detect subclinical atherosclerosis in patients with rheumatoid arthritis. Ann Rheum Dis. 72(11): 1764-7170.

Onut R, Balanescu AP, Constantinescu D, Calmac L, Marinescu M, Dorobantu PM, 2012. Imaging atherosclerosisby carotid intima-media thicknessin vivo: how to, where and in whom? Maedica (Buchar). 7(2): 153-62.

Qu B and Qu T, 2015. Causes of changes in carotid intima-media thickness: a literature review. Cardiovascular Ultrasound. 13:46.

Han L, Bai X, Lin H, Sun X, Chen X, 2013. Gender differences in the relationship between age-related carotid intima-media thickness and cardiac diastolic functionina healthy Chinese population. J. Card Fail. 19(5):325-32.

Ceponiene I, Klumbiene J, Tamuleviciute-Prasciene E, Motiejunaite J, Sakyte E, Ceponis J, et al., 2015. Associations between risk factors in childhood (12-13 years) and adulthood (48-49 years) and subclinical atherosclerosis: the Kaunas Cardiovascular Risk Cohort Study. BMC Cardiovasc Disord. 15: 89.

Feairheller DL, Dia KM, Kashem MA, Thakkar SR, Veerabhadrappa P, Sturgeon KM, et al., 2014. Effects of moderate aerobicexercise training on vascular heal than d blood pressure in African Americans. J. Clin.

Hipertens (Greenwich). 16(7):504-10.

Taylor BA, Zaleski AL, Capizzi JA, Ballard KD, Troyanos C, Baggish AL, et al., 2014. Influence of chronic exercise on carotid atherosclerosis in marathon runners. BMJ Open. 4(2), e004498.

Chen Y, Xiong H, Wu D, Pirbhulal S, Tian X, Zhang R, et al, 2015. Relationship of short-term blood pressure variability with carotid intima-media thickness in hypertensive patients. Biomed Eng Online. 14:71.

Bianga Katchunga P, Mongane Irenge J, Canwa R, Matabaro A, Nsimire S, Kabunga Q., 2014. Carotid intima-media thickness in the Congolese hypertensive in South Kivu. Ann Cardiol Angeiol (Paris).

Bosevski M, 2011. Carotid IMT, in type2 diabetic patients: a survey on factors of influence. Prilozi. 32(2): 289-97.

Pirro M, Vaudo G, Lupattelli G, Pasqualini L, Mannarino MR, Schillaci G, et al. 2013. On-treatment C-reactive protein and HDL cholesterol levels in patients at intermediate cardiovascular risk: impact on carotid intima-media thickness. Life Sci. 2013;93(8):338-43.

Gruszfeld D, Weber M, Nowakowska-Rysz M, Janas R, Kozlik-Feldmann R, Xhonneux A, et al. Protein intake in infancy and carotid intima media thickness at 5 years-a secondary analysis from a randomized trial. Ann Nutr Metab. 2015;66(1):51-9.

Walus-Miarka M, Wojciechowska W, Miarka P, Kloch-Bade‚ ek M, Wozniakiewicz E, Cz arnecka D, et al., 2013. Intima-media thickness correlates with features of metabolic syndrome in young people with a clinical diagnosis of familial hypercholesterolaemia. Kardiol Pol. 71(6):566-72.

Bos S, Duvekot MH, Touw-Blommesteijn AC, Verhoeven AJ, Mulder MT, Watts GF, 2015. plaques and carotid intima media thickness in statin-treated patients with familial hypercholesterolemia. Atherosclerosis. 242(1):226-9.

Mostaza JM, Laho C, Salinero-Fort MA, deBurgos-Lunar C, Laguna F, Estirado E, et al, 2015. Carotid atherosclerosis severity inrelation to glycemic status: a cross sectional population study. Atherosclerosis. 242(2):377-82.

Shimizu Y, Nakazato M, Sato S, Koyamatsu J, Yamanashi H, Nagayoshi M, et al., 2015. Association between hemoglobin A1c and carotid atherosclerosis in rural community-dwelling elderly Japanese men. JPhysiol Anthropol. 34(1):16.

Lorenz MW, Price JF, Robertson C, Bots ML, Polak JF, Poppert H, et al., 2015. Carotid intima media thickness progression and risk of vascular events in people with diabetes: results from the PROG-IMT Collaboration. Diabetes Care. [Epub ahead of print].

Shimizu Y, Sato S, Koyamatsu J, Yamanashi H, Tamai M, Kadota K, et al., 2014. Subclinical carotid atherosclerosis and hyperuricemia in relation to renal impairment in a rural Japanese population: the Nagasaki Islands study. Atherosclerosis. 233(2):525-9.

Lee MJ, Shin DH, Kim SJ, Oh HJ, Yoo DE, Kim JK, et al., 2012. Visceral fat thickness is associated with carotid atherosclerosis in peritoneal dialysis patients. Obesity (Silver Spring). 20(6):1301-1307.

Barcellos CR, Lage SH, Rocha MP, Hayashida SA, Baracat EC, Romano A, et al., 2013. Polycystic ovary syndrome and obesity do not affect vascular parameters related to earl atherosclerosis in young women without glucose metabolism disturbances, arterial hypertension and severe abnormalities of lipid profile. Gynecol Endocrinol. 29(4):370-4.

Rampersaud E, Bielak LF, Parsa A, Shen H, Post W, Ryan KA, et al., 2008. The association of coronary artery calcification and carotid artery intima-media thickness with distinct, traditional coronary artery disease risk factors in asymptomatic adults. AmJEpidemiol. 168(9):1016-23.

Masi S, D’Ajuto F, Martin-Ruiz C, Kahn T, Wong A, Ghosh AK, et al., 2014. Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort. Eur Heart J. 35(46):3296-303.

Ragab SM, Safan MA, Badr EA, Ebeid OM., 2014. Haptoglobin genotypes polymorphism as a risk factor for subclinical atherosclerosis in beta thalassemia major children; a single center Egyptian study. Hematology. [Epub ahead of print].

Cunnington MS, Mayosi BM, Hall DH, Avery PJ, Farrall M, Vickers MA, et al., 2009. Novel genetic variants linked to coronary artery diseaseby genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes. Atherosclerosis. 203(1):41-4.

Sinha PK, Santr G, De D, Sah A, Biswas K, Bhattachary P, et al., 2012. Carotid intimamedia thicknessin type2diabetes mellitus patients with cardiac autonomic neuropathy. JAssoc Physicians India. 60:14-8.

Ikeda N, Gupta A, Dey N, Bose S, Shafique S, Arak T, et al., 2015. Improved correlation between carotid and coronary atherosclerosis SYNTAX score using automated ultrasound carotid bulb plaque IMT measurement. Ultrasound Med Biol. 41(5):1247-62.

Pacifico L, Anania C, Martino F, Cantisani V, Pascone R, Marcantonio A, et al., 2010. Functional and morphological vascular changes in pediatric nonalcoholic fatty liver disease. Hepatology. 52(5):1643-51.

Park YB, Ahn CW, Choi HK, Lee SH, In BH, Lee HC, et al., 2002. Atherosclerosis in rheumatoid arthritis: morphologic evidence obtainedby carotid ultrasound. Arthritis Rheum. 46(7):1714-9.

Troitzsch P, Paulista Markus MR, Dorr M, Felix SB, Junger M, Schminke U, et al., 2012. Psoriasis is associated with increased intima-media thickness-the Study of Health in Pomerania (SHIP). Atherosclerosis. 225(2):486-90.

Gravani F, Papadaki I, Ant pa E, Ne os A, Masselou K, Ioakeimidis D, et al., 2015. Subclinical atherosclerosis and impaired bone health in patients with primary Sjogren’s yndrome: prevalence, clinical and laboratory associations. ArthritisResTher. 17(1):99.

Evelein AM, Visseren FL, van der Ent CK, Grobbee DE, Uiterwaal CS., 2014. Allergies are associated with arterial changesin young children. EurJPrev Cardiol. [Epub ahead of print].

Loimaala A, Rontu R, Vuori I, Mercuri M, Lehtimaki T, Nenonen A, et al., 2006. Blood leukocyte count is a risk factor for intima-media thickening and subclinical carotid atherosclerosis in middle-aged men. Atherosclerosis. 188(2):363-9.

Schoffelen AF, de Groot E, Tempelman HA, Visseren FL, Hoepelman AI, Barth RE. 2015. Carotid intima media thickness in mainly female HIV-infected subjects in rural South Africa: association with cardiovascular but not HIV-related factors. Clin Infect Dis. [Epub ahead of print].

Qu B, Su J, Wang Z, Wang Y, Han X, Wang H, et al., 2015. Effect of H. Pylori infection on cytokine profiles and oxidative balance in subjects with chronic alcohol ingestion. PLoS One. 10(6), e0129352.

Hintsanen M, Elovainio M, Puttonen S, Kivimaki M, Lehtimaki T, Kahonen M, et al., 2008. Val/Met polymorphism of the COMT gene moderates the association between job strain and early atherosclerosis in young men. J Occup Environ Med. 50(6):649-57.

Michikawa T, Nishiwaki Y, Nomiyama T, Uemura T, O’Uchi T, Sakurai H, et al., 2008. Job strain and arteriosclerosis in Three different t pes of arteries among male Japanese factor workers. Scand J Work Environ Health. 34(1):48-54.

Camelo LV, Giatti L, Chor D, Griep RH, Bensenor IM, Santos IS, et al., 2015. Associations of life course socioeconomic position and job stress with carotid intima-media thickness. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Soc Sci Med. 141:91-9.

Rosvall M, Ostergren PO, Hedblad B, Isacsson SO, Janzon L, Berglund G., 2002. Work-related psychosocial factors and carotid atherosclerosis. IntJ Epidemiol. 31(6):1169-78.

Juonala M, Voipio A, Pahkala K, Viikari JS, Mikkila V, Kahonen M, et al., 2015. Childhood 25-OH vitamin D levels and carotid intima-media thicknessin adulthood: the cardiovascular riskin young Finns study. JClin Endocrinol Metab. 100(49):1469-76.

Baker CP, Kulkarni B, Radhakrishna KV, Charyulu MS, Gregson J, Matsuzaki M, et al., 2015. Is the Association between Vitamin D and Cardiovascular Disease Risk Confounded by Obesit? Evidence from the Andhra Pradesh Children and Parents Stud (APCAPS). PLoSOne. 10(6), e0129468. doi:10.1371/journal.pone.0129468eCollection2015.

Reis JP, von Mühlen D, Michos ED, Miller 3rd ER, Appel LJ, Araneta MR, et al., 2009. Serum vitamin D, parathyroid hormone levels, and carotid atherosclerosis. Atherosclerosis. 207(2):585-90.

Sander PO, Meurman JH, Jogestrand T, Nowak J, Soder B., 2009. Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in blood as markers for early atherosclerosis in subjects with chronic periodontitis. JPeriodontal Res. 44(4):452-8.

Kong X, Jia X, Wei Y, Cui M, Wang Z, Tang L, et al., 2012. Association between micro albuminuria and subclinical atherosclerosis evaluatedby carotid artery intima-media in elderly patients with normal renal function. BMC Nephrol. 13:37.

Aykas F, Solak Y, Erden A, Bulut K, Dogan S, Sarli B, et al., 2015. Persistence of cardiovascular risk factors in women with previous preeclampsia: a longterm follow-up study. JInvestig Med. 63:641-5.

Shimiu M, Furuso N, Mitsumoto F, Takaama K, Ura K, Hiramine S, et al., 2015. Subclinical carotid atherosclerosis and triglycerides predict the incidence of chronic kidney disease in the Japanese general population: results from the Kyushuand Okinawa Population Study (KOPS). Atherosclerosis. 238(2):207-12.

Bossuyt J, Vandekerckhove G, De Backer TL, Van de Velde S, Azermai M, Stevens AM, et al., 2015. Vascular dysregulation in normal-tension glaucoma is not affected by structure and function of the microcirculation or macrocirculation at rest: a case-control study. Medicine (Baltimore). 94(2), e425.




DOI: http://dx.doi.org/10.30742/jikw.v6i1.326

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