Effect Of Intaking High-Fat Diet On White Rat`s (Rattus norvegicus)Blood Lipid Profil
DOI:
https://doi.org/10.30742/jikw.v3i1.36Keywords:
lipid profile, high-fat diet.Abstract
Obesity and metabolic syndrom are characterized by dislipidemia. One of methods that is performed to increase body fat contents is by intaking of high-fat diet. The purpose of this study was to demonstrate the effect of a dietary intake of high-fat on the lipid profile (total cholesterol, HDL, LDL, and triacylglycerol) in white rat (Rattus norvegicus). This research was tested on 30 white rats that were divided into 2 randomized groups, and were treated for 4 weeks. Group 1 (K1) : was treated with standard diet, (K2) : with standard and high-fat diet. The results showed that intaking high-fat diet increases the total cholesterol content, triacylglycerol, LDL cholesterol, and decreases HDL cholesterol content.
References
Askandar, T, Setiawan, PB, Santoso, D, Soegiharto, G 2007, Buku ajar ilmu penyakit dalam, Surabaya : Airlangga University Press.
NCEP ATP III, 2001, ‘Detection, evaluation, and treatment of high blood cholesterolin adults’, Circulation, 2001.
Bahri, A 2004, Dislipidemia sebagai faktor resiko penyakit jantung koroner, diunduh (Januari, 2012), e-USU Repositor, http://dokter-medis.blogspot.com
Ganong, WF., 2008, Buku ajar fisiologi kedokteran edisi 22. EGC, Jakarta.
Grundy, SM 1991, ‘Multifactorial etiology of hypercholesterolemia; implication for prevention of coronary heart disease’ Arteriosclerosis and Thrombosis 11, pp: 1619-1635.
Kusumawati, 2004, Bersahabat dengan hewan coba, Yogyakarta: Gajah Mada University Press.
Sugiyono, 2007, Metode penelitian kuantitatif dan kualitati, Bandung: Alfabeta, hal. 82
Zainuddin, M 2000, Metodologi penelitian, Surabaya: Program Pasca Sarjana Universitas Airlangga.
Federer, WT 1955, Experimental design: Theory and application. MacMilan. New York. Dalam Hanafiah, K.A 1995. Rancangan percobaan teori dan aplikasi, PT Raja Grafindo Persada, Jakarta.
Santoso, S 2012, Aplikasi SPSS pada statistik multivarian Jakarta : Elex Media Komputindo
Sopiyudin, D 2011, Statistik untuk kedokteran dan kesehatan, Jakarta : Salemba Medika.
Guyton, AC, and Hall, JE., 2006, Textbook of medical physiology11th ed, Elsevier Inc. Philadelphia.
Murray, RK., 2009, Harper’s illustrated biochemistry 28ed, USA: Mc.Graw Hill Company, Inc.
Fox, 2003, Human physiology 8th edition. The MacGraw-Hill Companies.
Sherwood, L., 2010, Human physiology from cells to systems, Canada: Brooks/cole Cengange Learning.
Marks, DB, Allan, D, Smith, CM, 2000, Biokimia kedokteran dasar: sebuah pendekatan klinis, Jakarta: EGC.
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