Giant Congenital Melanocytic Nevi (GCMN): Sebuah Laporan Kasus Langka

Erico Lemuel Yonathan, Hari Darmawan

Abstract


Giant Congenital Melanocytic Nevi (GCMN) is a nevus which present at birth or arise within the first few weeks of life. Incidence of GCMN is estimated at below 1:20.000 newborns. Lesion of GCMN usually appears with a black or brownish plaque and may have abnormal borders, flat or protruding surface and hypertrichosis. Giant Congenital Melanocytic Nevi (GCMN) is associated with malignant melanoma and neurocutaneous melanocytosis. A male newborn baby is reported to have a giant black hairy plaque, with irregular shape in his head since born. Patient was born naturally, full term, and normal birth weight. The mother has no medication consumption and disease history during pregnancy. In our three years follow up, there are multiple black patches with smaller size in front right and left leg, and the back of the body. The GCMN treatment consists of surgical and non-surgical procedures, psychological support, and lifelong monitoring. In this case, further examination and observation are needed.


Keywords


giant congenital melanocytic nevi; melanoma maligna; neurokutaneus melanositosis

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References


Abubakar Y, Ahmad HR, and Faruk JA, 2018. Giant Congenital Melanocytic Nevi: Case Report and Review of Literature. Sub-Saharan African Journal of Medicine. 5 (4): 138-141.

Araujo C, Resende C, Pardal F, and Brito C, 2015. Giant Congenital Melanocytic Nevi and Neurocutaneous Melanosis. Case Reports in Medicine. 2015: 1-6.

Balomenou F, Palianopoulos T, Drougia A, and Giapros V, 2019. Congenital Melanocytic Nevus: A Case Study and Review of the Literature. Journal of Case Reports. 9 (1): 67-69.

Endomba FT, Mbega CR, Tochie JN, and Petnga SJN, 2018. Giant congenital melanocytic nevus in a Cameroonian child: A case report. Journal of Medical Case Reports. 12 (175): 1-4.

Griffiths CEM, Barker J, Bleiker T, Chalmers R, and Creamer D, 2016. Congenital Naevi and other Developmental Abnormalities Affecting the Skin. Rook’s Textbook of Dermatology 9th ed. Blackwell Publishing, Oxford. 75.9-75.15.

Habif TP, 2004. Nevi and Malignant Melanoma. Clinical Dermatology: A Color Guide to Diagnosis and Therapy 6th ed. Mosby, Edinburgh. 858-861.

Hong SN, Huu ND, Duy NN, Trong TT, Bac HN, et al, 2019. Serial Excision for the Treatment of Giant Congenital Melanocytic Nevus: The Vietnamese Way. Open Access Macedonian Journal of Medical Sciences. 7 (2): 231-233.

James WD, Berger TG, and Elston DM, 2016. Melanocytic Nevi and Neoplasms. Andrews’ Diseases of the Skin Clinical Dermatology 12th ed. Elsevier, Philadelphia. 685-686.

Jewargikar R, Andola SK, and Gupta N, 2015. Giant congenital melanocytic nevus. Indian Journal of Paediatric Dermatology. 16: 214-216.

Meshram GG, Kaur N, and Hura KS, 2018. Giant Congenital Melanocytic Nevi: An Update and Emerging Therapies. Case Reports in Dermatology. 10: 24-28.

Sakhiya J, Sakhiya D, Patel M, and Daruwala F, 2020. Giant Congenital Melanocytic Nevi Successfully Treated with Combined Laser Therapy. Indian Dermatology Online Journal. 11: 79-82.

Viana ACL, Gontijo B, and Bittencourt FV, 2013. Giant congenital melanocytic nevus. An Bras Dermatol. 88 (6): 863-878.

Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, et al, 2012. Benign neoplasias and hiperplasias of melanocyte. Fitzpatrick’s Dermatology in General Medicine 8th ed. McGraw Hill, New York. 1377-1382.

Wolff K, Johnson RA, and Saavedra AP, 2013. Melanoma Precursors and Primary Cutaneous Melanoma. Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology 7th ed. McGraw Hill, New York. 253-255.

Wu M, Yu Q, Gao B, Sheng L, Li Q, et al, 2020. A large-scale collection of giant congenital melanocytic nevi: Clinical and histopathological characteristics. Experimental and Therapeutic Medicine. 19: 313-318.




DOI: http://dx.doi.org/10.30742/jikw.v10i1.1183

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