Response on THE Physical Function and Antrophometry of Lung TB Patiens by Regular Therapy and Food Intervention: a Preliminary Research

Budhi Setiawan, Ernawati Ernawati, Herni Suprapti

Abstract


Patients with active lung tuberculosis (TB) have low body mass index (BMI) because of a wasting. Changes in body weight during the initial period of TB therapy correlated with the death risk, illness severity and relapse as well as decrease of patient's physical function.

This study aimed to measure the effectiveness of soybean supplementation among TB patients with standard therapy in improving physical function and nutritional status. Fifty nine patients were randomly divided into two groups.

Intervention group received one hundred fifty gram nutritional supplementation and control group did not receive anything. Both groups were on the same regular antituberculosis treatment. Assessment of outcomes were done twice, before supplementation and then after 1 month of the treatment.

There were significant differences in the changes in proxy physical function parameter in the control and treatment group (3.16 ± 0.83 vs. 4.50 ± 1.47, P < 0.05) and changes in nutritional status variable (0.33 ± 0.15 vs. 0.47 ± 0.16, p < 0.05). However there was no significant difference in the change in mid upper arm circumference (0.83 ± 0.31 vs. 0.93 ± 0.31, p > 0.05). Further research is needed to confirm this result.

Keywords


TB, nutritional supplementation, standard therapy, body mass index, physical function

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References


World Health Organization. WHO Report 2011: Global Tuberculosis Control. Geneva : WHO.2011. http://whqlibdoc.who.int/publications/2011/9789241564380_eng.pdf diakses tanggal 7 Agustus 2013.

Lettow, V.M., W.W. Fawzi, R.D. Semba. Triple trouble: the role of malnutrition in tuberculosis and human immunodeficiency virus co-infection. Nutr. Rev. 2003. 61: 81–90.

Zachariah, R., M.P. Spielmann, A.D. Harries and F.M.Salaniponi. Moderate to severe malnutrition in patients with tuberculosis is a risk factor associated with early death. Trans. R. Soc. Trop. Med. Hyg. 2002. 96(3): 291-294.

Paton, N.I., Y.K Chua, A. Earnest, and C.B.E. Chee. Randomized controlled trial of nutritional supplementation in patients with newly diagnosed tuberculosis and wasting. The Am. J. of Clin. Nutr. 2004. 80(2): 460-465.

Gupta, K.B., R.Gupta, A. Atreja, M. Verma, and S. Vishvkarma. Tuberculosis and nutrition. Lung India : official organ of Indian Chest Society. 2009. 26(1), 9-16.

Villamor, E., E. Saathoff, F. Mugusi, R. J. Bosch, W. Urassa, and W.W. Fawzi. Wasting and body composition of adults with pulmonary tuberculosis in relation to HIV-coinfection, socioeconomic status, and severity of tuberculosis. Eur. J. of Clin. Nutr. 2006. 60(2): 163-171.

Sinclair, D., K. Abba, L. Grobler, and T.D.Sudarsanam. Nutritional supplements for people being treated for active tuberculosis. Cochrane Database of Systematic Reviews. 2011. Issue 11.

Setchell, K.D.R. Soy isoflavones - benefits and risks from nature’s selective estrogen receptor modulators (SERMs). J. Am. Coll. Nutr. 2001. 20: 354S–362S.

Taslim, N.A. Penyuluhan gizi, pemberian soy protein dan perbaikan status gizi penderita tuberculosis di Makassar. J. Med. Nus. 2004; 25: 59-64.

Astuti M., A. Meliala, F.S. Dalais, and M.L. Wahlqvist. Tempeh, a nutritious and healthy food from Indonesia. Asia Pacific Journal of Clinical Nutrition. 2000. 9(4): 322-325.

Erhardt, M.W., S. Muslimatun, and J.G. Erhardt. Fermented soyabean and vitamin C-rich fruit: a possibility to circumvent the further decrease of iron status among iron-deficient pregnant women in Indonesia. Public Health Nutrition. 2011. 14(12): 2185–2196.

Mahmud, Mien K., Hermana, and D.A Karyadi. preliminary study on the use of tempeh-based formula in the dietary treatment of chronic diarrhea. Majalah Kedokteran Indonesia (J. of the Indonesian Medical Association). 1985. 35(8): 443-446.

Hermana. [Effect of the consumption of food mixtures containing soybeans or tempeh on children under the age of five suffering from protein malnutrition]. PhD thesis, Fakultas Pasca Sarjana, Institut Pertanian Bogor, Bogor, Indonesia. 1983. xii + 105 p. Illust. No index. 28 cm. [84 ref. Ind].

Irawati, A., dan Rozanna R. Pemberian formula tempe pada penderita gizi buruk untuk mempercepat penyembuhan. Penelitian gizi dan makanan. 1994. 17: 89-97.

Utari, D.M. Efek intervensi tempe terhadap profil lipid, Superoksida Dismutase, LDL teroksidasi, dan Malondialdehyde pada wanita menopause. Disertasi doktor. Sekolah Pascasarjana Institut Pertanian Bogor. 2011.

Lukito, W. Candidate foods in the Asia–Pacific region for cardiovascular protection: nuts, soy, lentils and tempeh. Asia Pacific Journal of Clinical Nutrition. 2001. 10(2), 128–133.

PrayGod, G., N. Range, D. Faurholt-Jepsen, K. Jeremiah, M. Faurholt-Jepsen, M.G. Aabye, et al. Weight, body composition and handgrip strength among pulmonary tuberculosis patients: a matched cross-sectional study in Mwanza, Tanzania. Trans. R. Soc. Trop. Med. Hyg. 2011. 105(3): 140-147.

Layman, D.K. Dietary Guidelines should reflect new understandings about adult protein needs. Nutr & Met. 2009. 6: 12.

Hedger, J. N. Production of Tempeh, an Indonesian Fermented Food. Sourcebook of experiments for the teaching of microbiology, Primrose and Wardlaw (Eds). Academic Press. 1986. Pp: 597–602.

Thiele, S., and C. Weis. Consumer demand for food diversity: evidence for Germany. Food Policy. 2003. 28(2): 99–115.

Kennedy, N., A. Ramsay, L. Uiso, J.Gutmann, F.I. Ngowi, and S.H. Gillespie. Nutritional status and weight gain in patients with pulmonary tuberculosis in Tanzania. Trans. R. Soc. Trop. Med. Hyg. 1996. 90(2): 162-166.

Paton, N.I., Y.M. Ng, C.B.E. Chee, C. Persaud, and A.A. Jackson. The effects of tuberculosis and HIV infection on whole body protein metabolism during feeding measured by the [15N] glycine method. Am. J. Clin. Nutr. 2003. 78: 319–325.

Jahnavi, G., and C.H. Sudha. Randomised controlled trial of food supplements in patients with newly diagnosed tuberculosis and wasting. Singapore Med J. 2010. 51(12): 957-962.

Wyss, K., P. Kilima, and N. Lorenz. Costs of tuberculosis for households and health care providers in Dar es Salaam, Tanzania. Trop Med Int Health. 2001. 6(1), 60–68.

Dodor, E. Evaluation of nutritional status of new tuberculosis patients at the effia-nkwanta regional hospital. Ghana Med J. 2008. 42(1), 22-28.

Martins, N., P.S. Morris, and P.M. Kelly. Food incentives to improve completion of tuberculosis treatment: randomised controlled trial in Dili, Timor-Leste. Brit. Med. J. 2009. 26 (339): b4248.

Paton, N.I., and Y.M. Ng. Body composition studies in patients with wasting associated with tuberculosis. Nutrition. 2006. 22: 245–251.




DOI: http://dx.doi.org/10.30742/jikw.v3i2.18

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Jurnal Ilmiah Kedokteran Wijaya Kusuma 

ISSN: 1978-2071(print); 2580-5967 (online)
Fakultas Kedokteran 
Universitas Wijaya Kusuma Surabaya
Surabaya, Indonesia
 
Creative Commons License
All publications by Jurnal Ilmiah Kedokteran Wijaya Kusuma are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License