Effect of Submaximal Exercise on Trained and Untrained Intensity on Estrogen Levels in Female White Rats (Rattus Norvegicus) Wistar Strains
Abstract
Background: Trained and continuous physical activity can increase estrogen levels in women, while irregular activity can increase excessive Estrogen levels. Submaximal exercise is a recommended exercise to improve a woman's physiological function The purpose of this experiment was to determine the effect of submaximal exercise on trained and untrained intensity on Estrogen levels in female white rats (Rattus norvegicus) Wistar strains. Methods: This research was an experimental study using a post-test-only control group design using 30 female Wistar rats which were divided into 5 groups: control group not treated (K1), experimental group of animals with exercise intensity without intervention (K2), group of experimental animals with untrained intensity without intervention (K3), group of experimental animals with exercise intensity with intervention (K4), and experimental group of animals with exercise intensity with intervention (K4). experimental animals with untrained intensity treatment with intervention (K5). The intervention was swimming at moderate intensity with a duration of 85% of the maximum time to swim and a load of 8% of the rat's body weight. After the treatment period, all groups were terminated to take intracardiac blood measured using ELISA. Results: The data results were analyzed using statistical tests. The results of this study found that the trained group had lower Estrogen levels compared to the untrained group, but higher than the control group. The Kruskal-Wallis test show a significance value (p = 0.157), p> 0.05. Conclusion: In this study, there was no effect of submaximal exercise between trained and untrained intensity on Estrogen levels in Wistar strain female white rat.
Keywords
Full Text:
PDFReferences
Bebasari, E. (2017). Pengaruh Olahraga Teratur Terhadap Kadar Estrogen Adiposa dan Estrogen Serum pada Tikus Sprague dawley yang Dilakukan Ovariektomi. Jurnal Ilmu Kedokteran, 9(1), 17. https://doi.org/10.26891/jik.v9i1.2015.17-21
Carpentieri, A., Gamberi, T., Modesti, A., Amoresano, A., Colombini, B., Nocella, M., Bagni, M. A., Fiaschi, T., Barolo, L., Gulisano, M., &
Magherini, F. (2016). Profiling Carbonylated Proteins in Heart and
Skeletal Muscle Mitochondria from Trained and Untrained Mice. Journal of Proteome Research, 15(10), 3666–3678. https://doi.org/10.1021/acs.jproteome.6b00475
Daghigh, F., Alihemmati, A., Karimi, P., Habibi, P., & Ahmadiasl, N. (2018). Fibrotic and apoptotic markers alteration in ovariectomised rats: addition of swimming training preserves lung architecture. Archives of Physiology and Biochemistry, 124(4), 286–291. https://doi.org/10.1080/13813455.2017.1396347
Daiyah, I., Rizani, R., & Adella, E. R. (2021). Hubungan antara Aktivitas Fisik dan Indeks Massa Tubuh (IMT) dengan Kejadian Pre-Menstrual Syndrome Pada Remaja Putri. Jurnal Inovasi Penelitian, 2(7), 2273–2289. http://ir.nmapo.edu.ua:8080/bitstream/lib/3610/1/тези фінал.pdf
Fitriani, D. (2018). Peran Estrogen dan Leptin dalam Homeostasis Energi. Jurnal Ilmu Kedokteran Dan Kesehatan, 5. http://www.fao.org/3/I8739EN/i8739en.pdf%0Ahttp://dx.doi.org/10.1016/j.adolescence.2017.01.003%0Ahttp://dx.doi.org/10.1016/j.child
youth.2011.10.007%0Ahttps://www.tandfonline.com/doi/full/10.1080/23288604.2016.1224023%0Ahttp://pjx.sagepub.com/lookup/doi/10
Guyton, A. C., & Hall, J. E. (2014). Textbook of Medical Physiology ed.12.
Hita, I. P. A. D. (2020). Efektivitas Metode Latihan Aerobik dan Anaerobik untuk Menurunkan Tingkat Overweight dan Obesitas. Jurnal Penjakora, 7(2), 135. https://doi.org/10.23887/penjakora.v7i2.27375
Humaryanto. (2017). Deteksi Dini Osteoporosis Pasca Menopause. Jmj, 5(2), 164–177.
Lesmana, H. S., & Broto, E. P. (2019). Profil Glukosa Darah Sebelum, Setelah Latihan Fisik Submaksimal dan Selelah Fase Pemulihan Pada Mahasiswa FIK UNP. Media Ilmu Keolahragaan Indonesia, 8(2), 44–48. https://doi.org/10.15294/miki.v8i2.12726
Millah, H., Sudjarwo, I., & Subekti, N. (2018). Sosialisasi Aturan Berolahraga Yang Benar Sesuai Dengan Rumus “ TKPE ” ( Upaya Meningkatkan SDM Guru Olahraga SMA dan SMP di Lingkungan MGMP Kota Tasikmalaya ). Jurnal Pengabdian Siliwangi, 4(2), 157–160.
Moraska, A., Deak, T., Spencer, R. L., Roth, D., & Fleshner, M. (2000). Treadmill running produces both positive and negative physiological adaptations in Sprague-Dawley rats. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 279(4 48-4), 1321–1329. https://doi.org/10.1152/ajpregu.2000.279.4.r1321
Nyoman Kanca, I. (2015). Olahraga Dan Kesehatan Reproduksi. Medikora, 11(2), 205–218. https://doi.org/10.21831/medikora.v11i2.4765
Parwata, I. M. Y. (2015). Kelelahan dan Recovery Dalam Olahraga. Jurnal Pendidikan Kesehatan Rekreasi, 1, 2–13.
Permatasari, N., Kumala, Y. R., & Sulakso, T. (2017). Efek ekstrak daun ciplukan (Physalis minima L.) terhadap kadar malondialdehid tulang mandibula tikus (Rattus norvegicus) wistar pasca ovariektomi.
Prodenta Journal of Densitry, 1(1), 35–46.
Pizzino, G., Irrera, N., Cucinotta, M., Pallio, G., Mannino, F., Arcoraci, V., Squadrito, F., Altavilla, D., & Bitto, A. (2017). Oxidative Stress: Harms and Benefits for Human Health. Oxidative Medicine and Cellular Longevity, 2017. https://doi.org/10.1155/2017/8416763
Prasetya, R. E., Umijati, S., & Rejeki, P. (2018). Effect of Moderate Intensity Exercise on Body Weight and Blood Estrogen Level Ovariectomized Mice. Majalah Kedokteran Bandung, 50(3), 147–151. https://doi.org/10.15395/mkb.v50n3.1368
Pratama, N. R., Yunita, E., Ayuning, R., Fannasi, F., & Mada, U. G. (2011). Ekstrasksi Kulit Pisang Kepok (Musa paradisiaca L.) Sebagai Fitoestrogen Pada Perkembangan Kelenjer Payudara Tikus Terovariektomi Melalui Peningkatan Ekspresi C-Mye. Jurnal Saintifika, 3(1), 19–25.
Radtke, T., Nevitt, S. J., Hebestreit, H., & Kriemler, S. (2017). Physical exercise training for cystic fibrosis. Cochrane Database of Systematic Reviews, 2017(11). https://doi.org/10.1002/14651858.CD002768.pub4
Rahmawati. (2014). Pengaruh Latihan Fisik Maksimal Akut Terhadap Kadar Estradiol Tikus Putih Betina. Jurnal Ilmiah Universitas Batanghari Jambi, 14(3), 129–134.
Rietjens, I. M. C. M., Louisse, J., & Beekmann, K. (2017). The potential health effects of dietary phytoestrogens. British Journal of Pharmacology, 174(11), 1263–1280. https://doi.org/10.1111/bph.13622
Sugiritama, I. W., & Adiputra, I. N. (2019). Potensi Antosianin Dalam Manajemen Menopause. Jurnal Kesehatan Andalas, 8(1), 158. https://doi.org/10.25077/jka.v8i1.985
Swasta, E. (2012). Tahapan Fisiologi Reproduksi Wanita dan Pengaruh Olahraga. Universitas Negeri Yogyakarta.
Sylviana, N., Gunawan, H., Lesmana, R., Purba, A., & Akbar, I. B. (2017). The Effect of Astaxanthin and Regular Training on Dynamic Pattern of Oxidative Stress on Male under Strenuous Exercise. Indonesian Journal of Clinical Pharmacy, 6(1), 46–54. https://doi.org/10.15416/ijcp.2017.6.1.46
Utamayasa, I. G. D., Hanafi, M., & Rosmi, Y. F. (2022). Dampak dari Latihan Intensitas Sedang dan Intensitas Submaksimal terhadap Kebugaran Kardiorespirasi pada Wanita Muda. Jurnal Pendidikan Kesehatan Rekreasi, 8(2), 327–335.
Wardani, K., Yazir, Y., & Ilyas, S. (2012). Pengaruh Pemberian Vitamin E Terhadap Kadar Hormon Estrogen dan Gambaran Histopatologi Tulang Alveolar Mencit (Mus Musculus L) Yang Melakukan Latihan Fisik Maksimal. Dentika Dental Journal, 17(2), 140–144.
Yuslianti ER, 2018.Pengantar Radikal Bebas dan Antioksidan (Via Google Book). Sleman: Deepublish
DOI: http://dx.doi.org/10.30742/jikw.v13i1.2893
Refbacks
- There are currently no refbacks.
Copyright (c) 2024 Cinthya Fitri Paramitha, Mita Herdiyantini, Eric Mayo Dagradi, Annisa Ullya Rasyida
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Jurnal Ilmiah Kedokteran Wijaya Kusuma is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
