Effect Of Intaking High-Fat Diet On White Rat’s (Rattus norvegicus)Blood Lipid Profil
Abstract
Obesity and metabolic syndrom are characterized by dislipidemia. One of methods that is performed to increase body fat contents is by intaking of high-fat diet. The purpose of this study was to demonstrate the effect of a dietary intake of high-fat on the lipid profile (total cholesterol, HDL, LDL, and triacylglycerol) in white rat (Rattus norvegicus). This research was tested on 30 white rats that were divided into 2 randomized groups, and were treated for 4 weeks. Group 1 (K1) : was treated with standard diet, (K2) : with standard and high-fat diet. The results showed that intaking high-fat diet increases the total cholesterol content, triacylglycerol, LDL cholesterol, and decreases HDL cholesterol content.
Keywords
Full Text:
PDFReferences
Askandar, T, Setiawan, PB, Santoso, D, Soegiharto, G 2007, Buku ajar ilmu penyakit dalam, Surabaya : Airlangga University Press.
NCEP ATP III, 2001, ‘Detection, evaluation, and treatment of high blood cholesterolin adults’, Circulation, 2001.
Bahri, A 2004, Dislipidemia sebagai faktor resiko penyakit jantung koroner, diunduh (Januari, 2012), e-USU Repositor, http://dokter-medis.blogspot.com
Ganong, WF., 2008, Buku ajar fisiologi kedokteran edisi 22. EGC, Jakarta.
Grundy, SM 1991, ‘Multifactorial etiology of hypercholesterolemia; implication for prevention of coronary heart disease’ Arteriosclerosis and Thrombosis 11, pp: 1619-1635.
Kusumawati, 2004, Bersahabat dengan hewan coba, Yogyakarta: Gajah Mada University Press.
Sugiyono, 2007, Metode penelitian kuantitatif dan kualitati, Bandung: Alfabeta, hal. 82
Zainuddin, M 2000, Metodologi penelitian, Surabaya: Program Pasca Sarjana Universitas Airlangga.
Federer, WT 1955, Experimental design: Theory and application. MacMilan. New York. Dalam Hanafiah, K.A 1995. Rancangan percobaan teori dan aplikasi, PT Raja Grafindo Persada, Jakarta.
Santoso, S 2012, Aplikasi SPSS pada statistik multivarian Jakarta : Elex Media Komputindo
Sopiyudin, D 2011, Statistik untuk kedokteran dan kesehatan, Jakarta : Salemba Medika.
Guyton, AC, and Hall, JE., 2006, Textbook of medical physiology11th ed, Elsevier Inc. Philadelphia.
Murray, RK., 2009, Harper’s illustrated biochemistry 28ed, USA: Mc.Graw Hill Company, Inc.
Fox, 2003, Human physiology 8th edition. The MacGraw-Hill Companies.
Sherwood, L., 2010, Human physiology from cells to systems, Canada: Brooks/cole Cengange Learning.
Marks, DB, Allan, D, Smith, CM, 2000, Biokimia kedokteran dasar: sebuah pendekatan klinis, Jakarta: EGC.
DOI: http://dx.doi.org/10.30742/jikw.v3i1.36
Refbacks
- There are currently no refbacks.
Copyright (c) 2014 Made Subawa Harsa
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Jurnal Ilmiah Kedokteran Wijaya Kusuma is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License