Penyengatan Meningeal Sisterna Basalis Meningitis TB pada Computed Tomography Scanning: Sebuah Ulasan Bergambar

Anastasia Tjan, Made Widhi Asih, Elysanti Dwi Martadiani


Tuberculosis (TB) is one of the major worldwide threat and global burden in Indonesia. CNS tuberculosis is the most severe form of TB infection. CT evaluation on diagnosing tuberculosis meningitis (TBM) with triad of hydrocephalus, basal meningeal enhancement and infarction was reported to be sensitive. PCR cerebrospinal fluid (CSF) is known to be specific, however negative results have been reported due to presence of PCR’s inhibitors, poor lysis of mycobacteria, and the uneven distribution in specimens. CT Scan plays the vital role in diagnosing TBM patient with the presence of TBM CT triad, especially basal cistern enhancement (BME) which is the specific enhancement pattern in MTB patient. There are 9 must know BME pattern, such as contrast filling the cistern, double and triple line, linear enhancement at MCA cistern, Y sign, posterior infundibular recess enhancement, ill defined border, join the dots sign, nodular enhancement, and asymmetry off all pattern. Familiarizing BME criteria is essential to provide confident diagnosis and reduce morbidity and mortality


Meningitis; Tuberculosis; CT scan; neuroradiologi

Full Text:



Andres MM, Uy JAU, and Reyes-Paguia MP, 2016. Tuberculous Meningitis Basal Cistern Enhancement Pattern on CT imaging. TB Corner, 2(5):1-9

Andronikou S dan Wieselthaler N, 2004. Modern imaging of tuberculosis in children: thoracic, central nervous system and abdominal tuberculosis. Pediatric Radiology. 34(11): 861-875

Bhigjee A, Padayachee R, Paruk H., Hallwirth-Pillay K, Marais S dan Connoly C, 2007. Diagnosis of tuberculous meningitis: clinical and laboratory parameters. International Journal of Infectious Diseases. 11(4):348-354

Botha H, Ackerman C, Candy S, Carr J, Griffith-Richards S dan Bateman K, 2012. Reliability and Diagnostic Performance of CT Imaging Criteria in the Diagnosis of Tuberculous Meningitis. PLoS ONE. 7(6): e38982

Chawla K, Berwal A., Vishwanath S dan Shenoy V, 2017. Role of multiplex polymerase chain reaction in diagnosing tubercular meningitis. Journal of Laboratory Physicians. 9(2): 145.

Dil-Afroze, Mir A, Kirmani A, Shakeel-ul-Rehman, Eachkoti R dan Siddiqi M, 2008. Improved diagnosis of central nervous system tuberculosis by MPB64-Target PCR. Brazilian Journal of Microbiology. 39(2): 209-213.

Kementerian Kesehatan Republik Indonesia, 2018. Tuberkulosis.

Przybojewski S, Andronikou S dan Wilmshurst J, 2006. Objective CT criteria to determine the presence of abnormal basal enhancement in children with suspected tuberculous meningitis. Pediatric Radiology. 36(7): 687-696.

Raut T, Garg R, Jain A, Verma R, Singh M, Malhotra H, Kohli N dan Parihar A, 2013. Hydrocephalus in tuberculous meningitis: Incidence, its predictive factors and impact on the prognosis. Journal of Infection. 66(4): 330-337.

Sanei Taheri M, Karimi M, Haghighatkhah H, Pourghorban R, Samadian M dan Delavar Kasmaei H, 2015. Central Nervous System Tuberculosis: An Imaging-Focused Review of a Reemerging Disease. Radiology Research and Practice.1-8

Solari L, Soto A, Agapito J, Acurio V, Vargas D, Battaglioli T, Accinelli R, Gotuzzo E dan van der Stuyft P, 2013. The validity of cerebrospinal fluid parameters for the diagnosis of tuberculous meningitis. International Journal of Infectious Diseases. 17(12): e1111-e1115

Thwaites G, van Toor, R dan Schoeman J, 2013. Tuberculous meningitis: more questions, still too few answers. The Lancet Neurology. 12(10): 999-1010.



  • There are currently no refbacks.

Copyright (c) 2019 Anastasia Tjan

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.



Jurnal Ilmiah Kedokteran Wijaya Kusuma 

ISSN: 1978-2071(print); 2580-5967 (online)
Published by the Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya.
Surabaya, Indonesia
Creative Commons License
All publications by Jurnal Ilmiah Kedokteran Wijaya Kusuma are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
counter View My Stats